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Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a randomised, triple-blind, allocation concealed, placebo-controlled phase 2 trial.
Gorman, Ellen; Shankar-Hari, Manu; Hopkins, Phil; Tunnicliffe, William S; Perkins, Gavin D; Silversides, Jonathan; McGuigan, Peter; Jackson, Colette; Boyle, Roisin; McFerran, Jamie; McDowell, Cliona; Campbell, Christina; McFarland, Margaret; Smythe, Jon; Thompson, Jacqui; Williams, Barry; Curley, Gerard; Laffey, John G; Clarke, Mike; McAuley, Daniel F; O'Kane, Cecilia.
Afiliación
  • Gorman E; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.
  • Shankar-Hari M; Guy's and St Thomas' NHS Foundation Trust London, London, UK.
  • Hopkins P; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Tunnicliffe WS; Centre for Inflammation Research, The University of Edinburgh, Edinburgh, UK.
  • Perkins GD; Kings Trauma Centre, King's College London, London, UK.
  • Silversides J; Queen Elizabeth Hospital Birmingham, Birmingham, UK.
  • McGuigan P; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
  • Jackson C; University Hospitals Birmingham, Birmingham, UK.
  • Boyle R; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.
  • McFerran J; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, UK.
  • McDowell C; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, UK.
  • Campbell C; Northern Ireland Clinical Trials Unit, Belfast, UK.
  • McFarland M; Northern Ireland Clinical Trials Unit, Belfast, UK.
  • Smythe J; Northern Ireland Clinical Trials Unit, Belfast, UK.
  • Thompson J; Northern Ireland Clinical Trials Unit, Belfast, UK.
  • Williams B; Northern Ireland Clinical Trials Unit, Belfast, UK.
  • Curley G; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, UK.
  • Laffey JG; NHS Blood and Transplant Service, Oxford, UK.
  • Clarke M; NHS Blood and Transplant Service, Birmingham, UK.
  • McAuley DF; Independent Patient and Public Representative, Sherborne, UK.
  • O'Kane C; Royal College of Surgeons in Ireland, Dublin, Ireland.
Trials ; 23(1): 401, 2022 May 13.
Article en En | MEDLINE | ID: mdl-35562778
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Células Madre Mesenquimatosas / COVID-19 Tipo de estudio: Clinical_trials / Guideline Límite: Humans Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Células Madre Mesenquimatosas / COVID-19 Tipo de estudio: Clinical_trials / Guideline Límite: Humans Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2022 Tipo del documento: Article