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The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.
Kobialka, Piotr; Sabata, Helena; Vilalta, Odena; Gouveia, Leonor; Angulo-Urarte, Ana; Muixí, Laia; Zanoncello, Jasmina; Muñoz-Aznar, Oscar; Olaciregui, Nagore G; Fanlo, Lucia; Esteve-Codina, Anna; Lavarino, Cinzia; Javierre, Biola M; Celis, Veronica; Rovira, Carlota; López-Fernández, Susana; Baselga, Eulàlia; Mora, Jaume; Castillo, Sandra D; Graupera, Mariona.
Afiliación
  • Kobialka P; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Sabata H; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Vilalta O; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Gouveia L; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Angulo-Urarte A; Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
  • Muixí L; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Zanoncello J; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Muñoz-Aznar O; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Olaciregui NG; Developmental Tumor Biology Laboratory, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
  • Fanlo L; Developmental Tumor Biology Laboratory, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
  • Esteve-Codina A; 3D Chromatin Organization, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • Lavarino C; CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Javierre BM; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Celis V; Developmental Tumor Biology Laboratory, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
  • Rovira C; 3D Chromatin Organization, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • López-Fernández S; Pediatric Cancer Center Barcelona, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain.
  • Baselga E; Department of Pathology, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain.
  • Mora J; Department of Plastic Surgery, Hospital de la Santa Creu i de Sant Pau, Barcelona, Spain.
  • Castillo SD; Department of Dermatology, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Graupera M; Developmental Tumor Biology Laboratory, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
EMBO Mol Med ; 14(7): e15619, 2022 07 07.
Article en En | MEDLINE | ID: mdl-35695059
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Malformaciones Vasculares Límite: Animals Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: España
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Malformaciones Vasculares Límite: Animals Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: España