Pneumolysin suppresses the initial macrophage pro-inflammatory response to Streptococcus pneumoniae.

Periselneris, Jimstan; Turner, Carolin T; Ercoli, Giuseppe; Szylar, Gabriella; Weight, Caroline M; Thurston, Teresa; Whelan, Matthew; Tomlinson, Gillian; Noursadeghi, Mahdad; Brown, Jeremy

Pneumolysin suppresses the initial macrophage pro-inflammatory response to Streptococcus pneumoniae.

Periselneris, Jimstan; Turner, Carolin T; Ercoli, Giuseppe; Szylar, Gabriella; Weight, Caroline M; Thurston, Teresa; Whelan, Matthew; Tomlinson, Gillian; Noursadeghi, Mahdad; Brown, Jeremy.

Afiliación

Periselneris J; Centre for Inflammation and Tissue Repair, Division of Medicine, University College Medical School, London, UK.
Turner CT; Division of Infection and Immunity, University College London, London, UK.
Ercoli G; Centre for Inflammation and Tissue Repair, Division of Medicine, University College Medical School, London, UK.
Szylar G; Centre for Inflammation and Tissue Repair, Division of Medicine, University College Medical School, London, UK.
Weight CM; Division of Infection and Immunity, University College London, London, UK.
Thurston T; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK.
Whelan M; Division of Infection and Immunity, University College London, London, UK.
Tomlinson G; Division of Infection and Immunity, University College London, London, UK.
Noursadeghi M; Division of Infection and Immunity, University College London, London, UK.
Brown J; Centre for Inflammation and Tissue Repair, Division of Medicine, University College Medical School, London, UK.

Immunology ; 167(3): 413-427, 2022 11.

Article en En | MEDLINE | ID: mdl-35835695

Asunto(s)

Inflamasomas; Streptococcus pneumoniae; Animales; Antiinflamatorios; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Humanos; Interleucina-6; Macrófagos/metabolismo; Ratones; Estreptolisinas/genética; Estreptolisinas/metabolismo; Estreptolisinas/farmacología; Factores de Necrosis Tumoral; Factores de Virulencia

Palabras clave

Streptococcus pneumoniae; epithelial immunity; inflammation; pneumolysin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Streptococcus pneumoniae / Inflamasomas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Immunology Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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