Reduction in Insulin Mediated ERK Phosphorylation by Palmitate in Liver Cells Is Independent of Fatty Acid Induced ER Stress.

Mubarak, Sindiyan Alshaikh; Otaibi, Abeer Al; Qarni, Ali Al; Bakillah, Ahmed; Iqbal, Jahangir

Mubarak, Sindiyan Alshaikh; Otaibi, Abeer Al; Qarni, Ali Al; Bakillah, Ahmed; Iqbal, Jahangir.

Afiliación

Mubarak SA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Otaibi AA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Qarni AA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Bakillah A; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Iqbal J; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.

Nutrients ; 14(17)2022 Sep 02.

Article en En | MEDLINE | ID: mdl-36079898

Asunto(s)

Resistencia a la Insulina; Insulina; Estrés del Retículo Endoplásmico; Quinasas MAP Reguladas por Señal Extracelular/metabolismo; Ácidos Grasos/metabolismo; Glucosa/metabolismo; Humanos; Insulina/metabolismo; Insulina/farmacología; Hígado/metabolismo; Ácido Oléico/metabolismo; Ácido Oléico/farmacología; Palmitatos/metabolismo; Palmitatos/farmacología; Fosforilación; Proteínas Proto-Oncogénicas c-akt/metabolismo

Palabras clave

ER stress; insulin resistance; insulin signaling; oleate; palmitate; tunicamycin; unfolded protein response

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Insulina Límite: Humans Idioma: En Revista: Nutrients Año: 2022 Tipo del documento: Article País de afiliación: Arabia Saudita

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