Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3.

Shen, Tianyi; Miao, Suqin; Zhou, Yulin; Yi, Xiaoming; Xue, Song; Du, Bowen; Tang, Chaopeng; Qu, Le; Fu, Dian; Jia, Ruipeng; He, Haowei

Shen, Tianyi; Miao, Suqin; Zhou, Yulin; Yi, Xiaoming; Xue, Song; Du, Bowen; Tang, Chaopeng; Qu, Le; Fu, Dian; Jia, Ruipeng; He, Haowei.

Afiliación

Shen T; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Miao S; Department of Anesthesiology, Jinling Hospital, Nanjing University Medical School, Nanjing, 210002, Jiangsu, China.
Zhou Y; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Yi X; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Xue S; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Du B; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Tang C; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Qu L; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Fu D; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China.
Jia R; Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210002, Jiangsu, China. ruipengj@163.com.
He H; Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, 210002, Jiangsu, China. hohowell@gmail.com.

Cell Commun Signal ; 20(1): 152, 2022 09 24.

Article en En | MEDLINE | ID: mdl-36153596

Asunto(s)

Carcinoma de Células Renales; Exosomas; Neoplasias Renales; MicroARNs; ARN Largo no Codificante; Animales; Carcinoma de Células Renales/patología; Línea Celular Tumoral; Exosomas/metabolismo; Humanos; Interleucina-10/metabolismo; Neoplasias Renales/metabolismo; Activación de Macrófagos/genética; Macrófagos/metabolismo; Ratones; MicroARNs/genética; FN-kappa B/metabolismo; ARN Largo no Codificante/genética; ARN Largo no Codificante/metabolismo; ARN Mensajero/metabolismo; Factor de Transcripción STAT3/metabolismo; Factor de Crecimiento Transformador beta/metabolismo; Factores de Crecimiento Transformadores/metabolismo

Palabras clave

Clear cell renal cell carcinoma; Exosomes; Macrophage; NF-κB signaling pathway; STAT3; lncRNA AP000439.2

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / MicroARNs / Exosomas / ARN Largo no Codificante / Neoplasias Renales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Commun Signal Año: 2022 Tipo del documento: Article País de afiliación: China

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