Melatonin attenuates chronic stress-induced hippocampal inflammatory response and apoptosis by inhibiting ADAM17/TNF-&#945; axis.

Zhang, Haiyang; Wei, Mian; Sun, Ning; Wang, Hui; Fan, Honggang

Melatonin attenuates chronic stress-induced hippocampal inflammatory response and apoptosis by inhibiting ADAM17/TNF-α axis.

Zhang, Haiyang; Wei, Mian; Sun, Ning; Wang, Hui; Fan, Honggang.

Afiliación

Zhang H; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Wei M; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.
Sun N; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.
Wang H; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.
Fan H; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China. Electronic address: fanhonggang2002@163.com.

Food Chem Toxicol ; 169: 113441, 2022 Nov.

Article en En | MEDLINE | ID: mdl-36162616

Asunto(s)

Proteína ADAM17; Apoptosis; Hipocampo; Melatonina; Enfermedades Neuroinflamatorias; Fármacos Neuroprotectores; Estrés Psicológico; Animales; Ratas; Proteína ADAM17/antagonistas & inhibidores; Citocinas/metabolismo; Hipocampo/efectos de los fármacos; Hipocampo/patología; Melatonina/farmacología; Melatonina/uso terapéutico; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Talidomida/farmacología; Factor de Necrosis Tumoral alfa/metabolismo; Proteína p53 Supresora de Tumor/metabolismo; Enfermedades Neuroinflamatorias/tratamiento farmacológico; Enfermedades Neuroinflamatorias/etnología; Estrés Psicológico/complicaciones; Enfermedad Crónica

Palabras clave

Apoptosis; Chronic stress; Depression; Hippocampus; Inflammation; Melatonin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estrés Psicológico / Apoptosis / Fármacos Neuroprotectores / Proteína ADAM17 / Enfermedades Neuroinflamatorias / Hipocampo / Melatonina Límite: Animals Idioma: En Revista: Food Chem Toxicol Año: 2022 Tipo del documento: Article País de afiliación: China

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