Methionine 274 Is Not the Determining Factor for Selective Inhibition of Histone Deacetylase 8 (HDAC8) by L-Shaped Inhibitors.

Jänsch, Niklas; Lang, Kim Leoni; Meyer-Almes, Franz-Josef

Jänsch, Niklas; Lang, Kim Leoni; Meyer-Almes, Franz-Josef.

Afiliación

Jänsch N; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Haardtring 100, 64295 Darmstadt, Germany.
Lang KL; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Haardtring 100, 64295 Darmstadt, Germany.
Meyer-Almes FJ; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Haardtring 100, 64295 Darmstadt, Germany.

Int J Mol Sci ; 23(19)2022 Oct 04.

Article en En | MEDLINE | ID: mdl-36233076

Asunto(s)

Inhibidores de Histona Desacetilasas; Neuroblastoma; Inhibidores de Histona Desacetilasas/química; Histona Desacetilasas/metabolismo; Humanos; Isoenzimas; Metionina; Proteínas Represoras

Palabras clave

HDAC inhibitors; HDAC8 muteins; binding selectivity; thermo stability

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Histona Desacetilasas / Neuroblastoma Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Alemania

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