Fulminant Course of Acute Necrotizing Encephalopathy Followed by Serial MRI: A Case Report.
Taehan Yongsang Uihakhoe Chi
; 82(5): 1274-1280, 2021 Sep.
Article
en En
| MEDLINE
| ID: mdl-36238398
ABSTRACT
Acute necrotizing encephalopathy (ANE) is a rare but distinctive type of influenza-associated encephalopathy characterized by symmetric multiple lesions with an invariable thalamic involvement. Although the exact pathogenesis of ANE remains unclear, the most prevalent hypothesis is the "cytokine storm," which results in blood-brain-barrier breakdown. We present the case of a 10-year-old boy with fulminant ANE confirmed with serial MRI studies, including diffusion-weighted imaging and susceptibility-weighted imaging. A comparison of these serial images demonstrated detailed and longitudinal changes in MRI findings during the clinical course corresponding to pathophysiological changes. Our case clarifies the pathogenesis of ANE brain lesions using serial imaging studies and suggests that early immunomodulatory therapy reduces brain damage.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Taehan Yongsang Uihakhoe Chi
Año:
2021
Tipo del documento:
Article