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Novel polymorphism at KLF15 gene and its association with growth traits in Hu sheep.
Zhai, Rui; Wang, Weimin; Zhang, Deyin; Li, Xiaolong; Zhang, Yukun; Zhao, Yuan; Zhao, Liming; Wang, Jianghui; Xu, Dan; Cheng, Jiangbo; Li, Wenxin; Zhou, Bubo; Lin, Changchun; Zeng, Xiwen; Yang, Xiaobin; Ma, Zongwu; Liu, Jia; Cui, Panpan; Zhang, Xiao Xue.
Afiliación
  • Zhai R; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Wang W; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhang D; The State Key Laboratory of Grassland Agro-Ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu, China.
  • Li X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhang Y; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhao Y; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhao L; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Wang J; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Xu D; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Cheng J; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Li W; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhou B; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Lin C; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zeng X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Yang X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Ma Z; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Liu J; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Cui P; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
  • Zhang XX; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
Anim Biotechnol ; : 1-7, 2022 Nov 08.
Article en En | MEDLINE | ID: mdl-36346056
ABSTRACT
Growth traits are important economic characteristics of livestock and poultry. In the present study, the expression features of KLF15 and the relationship between KLF15 gene polymorphisms and growth traits in Hu sheep were investigated by using real-time quantitative PCR technology (qPCR), Sanger sequencing, and Kaspar genotyping technology. The qPCR results showed that the KLF15 gene is expressed widely in the tested tissues of Hu sheep, and the expression level of the KLF15 gene in the heart and the muscle was significantly higher than in other tissues (p < 0.05). Missense mutation c.62565119 A > G was found in KLF15, and an association analysis showed that it was correlated with the growth traits (body weight, body height, and body length) of Hu sheep (p < 0.05). The body weight, body height, and body length of the sheep carrying the AA genotype were remarkably higher than those of the GG and AG genotypes (p < 0.05). These results showed that novel polymorphisms at the KLF15 gene can be used as a genetic marker of growth traits of Hu sheep.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China