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RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Strecker, Jonathan; Demircioglu, F Esra; Li, David; Faure, Guilhem; Wilkinson, Max E; Gootenberg, Jonathan S; Abudayyeh, Omar O; Nishimasu, Hiroshi; Macrae, Rhiannon K; Zhang, Feng.
Afiliación
  • Strecker J; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Demircioglu FE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Li D; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Faure G; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Wilkinson ME; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Gootenberg JS; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Abudayyeh OO; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Nishimasu H; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Macrae RK; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Zhang F; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Science ; 378(6622): 874-881, 2022 11 25.
Article en En | MEDLINE | ID: mdl-36423276

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Proteínas Bacterianas / ARN Guía de Kinetoplastida / Deltaproteobacteria / Proteolisis / Proteínas Asociadas a CRISPR / Sistemas CRISPR-Cas Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Proteínas Bacterianas / ARN Guía de Kinetoplastida / Deltaproteobacteria / Proteolisis / Proteínas Asociadas a CRISPR / Sistemas CRISPR-Cas Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos