A Deep Dive into the Circulating ctDNA Cosmos to Vanquish Neuroblastoma.
Cancer Discov
; 12(12): 2727-2729, 2022 12 02.
Article
en En
| MEDLINE
| ID: mdl-36458435
ABSTRACT
SUMMARY:
Single biopsies fail to reflect intratumor heterogeneity and tumor evolution. In this issue of Cancer Discovery, Bosse and colleagues show an important role for circulating cell-free tumor DNA sequencing to detect the genomic evolution of neuroblastoma under ALK inhibitor therapy and identify novel (sub)clonal pathogenic variants involved in disease progression under conventional therapy. See related article by Bosse et al., p. 2800 (5).
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ácidos Nucleicos Libres de Células
/
ADN Tumoral Circulante
/
Neuroblastoma
Límite:
Humans
Idioma:
En
Revista:
Cancer Discov
Año:
2022
Tipo del documento:
Article
País de afiliación:
Alemania