Preliminary study to classify mechanisms of mitochondrial toxicity by in vitro metabolomics and bioinformatics.

Hibino, Yui; Iguchi, Akira; Zaitsu, Kei

Hibino, Yui; Iguchi, Akira; Zaitsu, Kei.

Afiliación

Hibino Y; Safety Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Shonan Health Innovation Park, 2-26-1, Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan; Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
Iguchi A; Geological Survey of Japan, National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Central 7, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8567, Japan.
Zaitsu K; Multimodal Informatics and Wide-data Analytics Laboratory, Department of Computational Systems Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, 930 Nishi Mitani, Kinokawa, Wakayama 649-6493, Japan; In Vivo Real-time Omics Laboratory, Institute for Advanced Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. Electronic address: temporary.mail.kz@gmail.com.

Toxicol Appl Pharmacol ; : 116316, 2022 Nov 14.

Article en En | MEDLINE | ID: mdl-36462684

Palabras clave

Bioinformatics; Gas chromatography-mass spectrometry; HepG2 cells; Hepatocyte; Metabolomics; Mitochondrial toxicants

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Japón

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