Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT.
Health Technol Assess
; 26(48): 1-162, 2022 12.
Article
en En
| MEDLINE
| ID: mdl-36524582
ABSTRACT
BACKGROUND: Lung cancer is a common cause of cancer death worldwide. If the disease is caught early, the part of the lung containing the tumour can be removed in an operation called a lobectomy. The operation can be carried out through a large cut so that the surgeon has a full view of the lung, which is called open surgery, or using several small cuts and a camera, which is called video-assisted thoracoscopic (keyhole) surgery. It is thought that, as keyhole surgery is less invasive, patients recover quicker. However, to the best of our knowledge, there are no high-quality research studies that are applicable to UK practice to support this. This study was conducted so that it could be determined, based on high-quality evidence, which operation provides the best treatment and recovery for patients. WHO PARTICIPATED?: Five hundred and three adults referred for lobectomy for known or suspected lung cancer from nine hospitals in the UK. WHAT WAS INVOLVED?: Participants were randomly allocated to either receive keyhole or open surgery. Participants were followed up for 12 months. We collected information on further treatment, hospital visits, safety information and disease progression over this period. Participants were also asked to complete questionnaires about their health and recovery. WHAT DID THE TRIAL FIND?: For patients with early-stage lung cancer who underwent a lobectomy, keyhole surgery led to less pain, less time in hospital and better quality of life than open surgery, without having a detrimental effect on cancer progression or survival. Keyhole surgery was found to be cost-effective and to provide excellent value for money for the NHS.
Palabras clave
ANALGESIA; BIOPSY; CARDIOTHORACIC SURGERY; COST-BENEFIT ANALYSIS; DISEASE PROGRESSION; DISEASE-FREE SURVIVAL; FROZEN SECTIONS; INFORMED CONSENT; INTENTION TO TREAT ANALYSIS; LENGTH OF STAY; LOBECTOMY; LUNG CANCER; MINIMALLY INVASIVE; ONCOLOGY; OPEN SURGERY; PAIN; PAIN MEASUREMENT; PATIENT REPORTED OUTCOME MEASURES; QUALITY OF LIFE; QUALITY-ADJUSTED LIFE YEARS; RANDOMISED CONTROLLED TRIAL; RESPIRATORY MEDICINE; SURGERY; SURVEYS AND QUESTIONNAIRES; THORACIC SURGERY; THORACOTOMY; VATS LOBECTOMY; VIDEO ASSISTED; VIDEO-ASSISTED
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cirugía Torácica Asistida por Video
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Neoplasias Pulmonares
Tipo de estudio:
Clinical_trials
/
Etiology_studies
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Health_technology_assessment
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Health Technol Assess
Asunto de la revista:
PESQUISA EM SERVICOS DE SAUDE
/
TECNOLOGIA MEDICA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Reino Unido