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Advancing drug discovery for glomerulopathies using stem-cell-derived kidney models.
Barreto, Amanda D; Burt, Morgan A; Musah, Samira.
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  • Barreto AD; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Center for Biomolecular and Tissue Engineering, Duke University, Durham, NC 27708, USA.
  • Burt MA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
  • Musah S; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Department of Medicine, Division of Nephrology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Cell Biology, Duke University, Durham, NC 27710, USA; Center for Biomolecular and Tissue Engineering, Duke University, Durham, NC 27708, USA; Developmental and Stem Cell Biology Program, Duke MEDx Investigator, Duke University, Durham, NC 27710, USA; Duke Regeneration Center, Duke University, Durham,
Trends Pharmacol Sci ; 44(4): 204-207, 2023 04.
Article en En | MEDLINE | ID: mdl-36566132
ABSTRACT
Chronic kidney disease (CKD) is an epidemic that affects millions worldwide. The glomerulus, a specialized unit of the nephron, is highly susceptible to injury. Human induced pluripotent stem cells (iPSCs) have emerged as an attractive resource for modeling kidney disease and therapeutic discovery.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Enfermedades Renales Límite: Humans Idioma: En Revista: Trends Pharmacol Sci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Enfermedades Renales Límite: Humans Idioma: En Revista: Trends Pharmacol Sci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos