Effects of a 12-week Vivifrail exercise program on intrinsic capacity among frail cognitively impaired community-dwelling older adults: secondary analysis of a multicentre randomised clinical trial.
Age Ageing
; 51(12)2022 12 05.
Article
en En
| MEDLINE
| ID: mdl-36580558
ABSTRACT
INTRODUCTION:
The World Health Organisation recently defined the construct of intrinsic capacity (IC), a function-based marker of older adult's health encompassing all mental and physical capacities of the individual. Multicomponent physical exercise (MCE) is a potential intervention capable to maintain/increase IC at older age; however, evidence is scarce on the effects of MCE on IC in cognitively impaired pre-frail/frail older adults.METHODS:
Secondary analyses of a randomised clinical trial. One hundred and eighty-eight older outpatients (age = 84.06 ± 4.77, 70.2% women) presenting with pre-frailty/frailty (according to Fried Criteria) and mild cognitive impairment (MCI)/mild dementia were recruited in the Geriatric clinics of three tertiary hospitals in Spain. Subjects were randomised to participate in the 12-week home-based individualised Vivifrail MCE or usual care. An IC index was created based on the z-score of the locomotion (Short Physical Performance Battery), cognitive (Montreal Cognitive Assessment), psychology (15-item Geriatric Depression Scale Yesavage) and vitality (handgrip strength) domains.RESULTS:
After the 3-month intervention, linear mixed models showed significant between-group differences in the evolution of the IC composite score (ß=0.48; 95% confidence interval [CI] = 0.24, 0.74; P < 0.001), IC Locomotion (ß = 0.42; 95% CI = 0.10, 0.74; P < 0.001), IC Cognition (ß = 0.45; 95% CI = 0.03, 0.87; P < 0.05) and IC Vitality domains (ß = 0.50; 95% CI = 0.25, 0.74 at 3-month) favouring the MCE group.CONCLUSIONS:
The 12-week Vivifrail multicomponent exercise program is an effective strategy to enhance IC, especially in terms of locomotion, cognition and vitality IC domains in community-dwelling older adults with pre-frailty/frailty and MCI/mild dementia, compared to usual care.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Demencia
/
Fragilidad
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
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Prognostic_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Age Ageing
Año:
2022
Tipo del documento:
Article
País de afiliación:
Francia