The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands.

Bhuma, Naresh; Chand, Karam; Andréasson, Måns; Mason, James; Das, Rabindra Nath; Patel, Ankit Kumar; Öhlund, Daniel; Chorell, Erik

Bhuma, Naresh; Chand, Karam; Andréasson, Måns; Mason, James; Das, Rabindra Nath; Patel, Ankit Kumar; Öhlund, Daniel; Chorell, Erik.

Afiliación

Bhuma N; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden.
Chand K; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden; Department of Medicinal Chemistry, Uppsala University, BMC, 751 23, Uppsala, Sweden.
Andréasson M; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden.
Mason J; Department of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden; Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Das RN; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, 603 203, Tamil Nadu, India.
Patel AK; Department of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden; Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Öhlund D; Department of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden; Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Chorell E; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden. Electronic address: erik.chorell@umu.se.

Eur J Med Chem ; 248: 115103, 2023 Feb 15.

Article en En | MEDLINE | ID: mdl-36645982

Asunto(s)

G-Cuádruplex; Ligandos; ADN/metabolismo; Oncogenes; Pirimidinas

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: G-Cuádruplex Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Suecia

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