Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity.
JHEP Rep
; 5(2): 100615, 2023 Feb.
Article
en En
| MEDLINE
| ID: mdl-36687468
AUROC, area under the receiver operating characteristic curve; ECM, extracellular matrix; HSC, hepatic stellate cells; LSM, liver stiffness measurement; MCP, matricellular protein; NAFL, non-alcoholic fatty liver; NAFLD; NAFLD, non-alcoholic fatty liver disease; NAS, NAFLD activity score; NASH; PCA, principal component analysis; SAF, steatosis, activity, and fibrosis; SE, sensitivity; SMOC2; SMOC2, SPARC-related modular calcium-binding protein 2; SP, specificity; SPARC, secreted protein acidic and cysteine-rich; VSMCs, vascular smooth muscle cells; WGCNA, weighted gene co-expression network analysis; aHSC, activated HSC; hepatic stellate cells; non-invasive biomarker; qHSC, quiescent HSC; smFISH, single-molecule fluorescence in situ hybridisation; transcriptomics
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
JHEP Rep
Año:
2023
Tipo del documento:
Article
País de afiliación:
Dinamarca