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Extracellular vesicles and nanoparticles: emerging complexities.
Jeppesen, Dennis K; Zhang, Qin; Franklin, Jeffrey L; Coffey, Robert J.
Afiliación
  • Jeppesen DK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Zhang Q; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Franklin JL; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Coffey RJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: robert.coffey@vumc.org.
Trends Cell Biol ; 33(8): 667-681, 2023 08.
Article en En | MEDLINE | ID: mdl-36737375
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding because recent discoveries have revealed a much greater complexity and diversity than was appreciated only a few years ago. New types of EVs and NPs have recently been described. Proteins and nucleic acids previously thought to be packaged in exosomes appear to be more enriched in different types of EVs and in two recently identified amembranous NPs, exomeres and supermeres. Thus, our understanding of the cell biology and intercellular communication facilitated by the release of EVs and NPs is in a state of flux. In this review, we describe the different types of EVs and NPs, highlight recent advances, and present major outstanding questions.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Nucleicos / Exosomas / Vesículas Extracelulares Límite: Humans Idioma: En Revista: Trends Cell Biol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Nucleicos / Exosomas / Vesículas Extracelulares Límite: Humans Idioma: En Revista: Trends Cell Biol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos