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Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models.
Xu, Pengfei; Yang, Joy C; Ning, Shu; Chen, Bo; Nip, Christopher; Wei, Qiang; Liu, Liangren; Johnson, Oleta T; Gao, Allen C; Gestwicki, Jason E; Evans, Christopher P; Liu, Chengfei.
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  • Xu P; Department of Urologic Surgery, University of California, Davis, CA, USA.
  • Yang JC; Department of Urologic Surgery, University of California, Davis, CA, USA.
  • Ning S; Department of Urologic Surgery, University of California, Davis, CA, USA.
  • Chen B; Department of Urologic Surgery, University of California, Davis, CA, USA; Department of Urology, West China Hospital, Sichuan University, Sichuan, China.
  • Nip C; Department of Urologic Surgery, University of California, Davis, CA, USA.
  • Wei Q; Department of Urology, West China Hospital, Sichuan University, Sichuan, China.
  • Liu L; Department of Urology, West China Hospital, Sichuan University, Sichuan, China.
  • Johnson OT; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Gao AC; Department of Urologic Surgery, University of California, Davis, CA, USA; University of California, Davis Comprehensive Cancer Center, CA, USA.
  • Gestwicki JE; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Evans CP; Department of Urologic Surgery, University of California, Davis, CA, USA; University of California, Davis Comprehensive Cancer Center, CA, USA.
  • Liu C; Department of Urologic Surgery, University of California, Davis, CA, USA; University of California, Davis Comprehensive Cancer Center, CA, USA. Electronic address: cffliu@ucdavis.edu.
Pharmacol Res ; 189: 106692, 2023 03.
Article en En | MEDLINE | ID: mdl-36773708
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Androgénicos / Neoplasias de la Próstata Resistentes a la Castración Límite: Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Androgénicos / Neoplasias de la Próstata Resistentes a la Castración Límite: Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos