Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2&#945; Burst in the Brain of PTZ-Treated Rats.

Pazarlar, Burcu Azak; Egilmez, Cansu Bilister; Erdogan, Mumin Alper; Erbas, Oytun

Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2α Burst in the Brain of PTZ-Treated Rats.

Pazarlar, Burcu Azak; Egilmez, Cansu Bilister; Erdogan, Mumin Alper; Erbas, Oytun.

Afiliación

Pazarlar BA; Faculty of Medicine, Department of Physiology, Izmir Katip Celebi University, 35620, Izmir, Turkey. burcuazak@hotmail.com.
Egilmez CB; Faculty of Medicine, Department of Physiology, Izmir Katip Celebi University, 35620, Izmir, Turkey.
Erdogan MA; Faculty of Medicine, Department of Physiology, Izmir Katip Celebi University, 35620, Izmir, Turkey.
Erbas O; Faculty of Medicine, Department of Physiology, Bilim University, Istanbul, Turkey.

Neurochem Res ; 48(6): 1971-1980, 2023 Jun.

Article en En | MEDLINE | ID: mdl-36780043

Asunto(s)

Epilepsia; Pentilenotetrazol; Humanos; Ratas; Animales; Pentilenotetrazol/toxicidad; Tacrolimus/farmacología; Tacrolimus/uso terapéutico; Dinoprost; Inmunosupresores/uso terapéutico; Inmunosupresores/farmacología; Tiempo de Tratamiento; Convulsiones/inducido químicamente; Convulsiones/tratamiento farmacológico; Encéfalo/metabolismo; Epilepsia/tratamiento farmacológico; Estrés Oxidativo; Superóxido Dismutasa/metabolismo; Modelos Animales de Enfermedad; Anticonvulsivantes/uso terapéutico

Palabras clave

Epilepsy; Oxidative stress; PGF2α; Pentylenetetrazol; Tacrolimus

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pentilenotetrazol / Epilepsia Límite: Animals / Humans Idioma: En Revista: Neurochem Res Año: 2023 Tipo del documento: Article País de afiliación: Turquía

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google