The anxiolytic drug opipramol inhibits insulin-induced lipogenesis in fat cells and insulin secretion in pancreatic islets.

Iglesias-Osma, Maria Carmen; García-Barrado, Maria José; Hernandez-Gonzalez, David; Perrier, Kévin; Viana, Pénélope; Carpéné, Christian

Iglesias-Osma, Maria Carmen; García-Barrado, Maria José; Hernandez-Gonzalez, David; Perrier, Kévin; Viana, Pénélope; Carpéné, Christian.

Afiliación

Iglesias-Osma MC; Department of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
García-Barrado MJ; Laboratory of Neuroendocrinology, Institute of Neurosciences of Castilla y León (INCyL), and Laboratory of Neuroendocrinology and Obesity, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Hernandez-Gonzalez D; Department of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Perrier K; Laboratory of Neuroendocrinology, Institute of Neurosciences of Castilla y León (INCyL), and Laboratory of Neuroendocrinology and Obesity, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Viana P; Department of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Carpéné C; Laboratory of Neuroendocrinology, Institute of Neurosciences of Castilla y León (INCyL), and Laboratory of Neuroendocrinology and Obesity, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.

J Physiol Biochem ; 79(2): 415-425, 2023 May.

Article en En | MEDLINE | ID: mdl-36821072

Asunto(s)

Ansiolíticos; Islotes Pancreáticos; Opipramol; Humanos; Ratas; Ratones; Animales; Insulina/metabolismo; Secreción de Insulina; Opipramol/metabolismo; Opipramol/farmacología; Ansiolíticos/farmacología; Ansiolíticos/metabolismo; Lipogénesis; Colforsina/farmacología; Colforsina/metabolismo; Islotes Pancreáticos/metabolismo; Adipocitos/metabolismo; Lipólisis; Glucosa/metabolismo; Lípidos/farmacología

Palabras clave

Adipose tissue; Antidepressants; Antipsychotics; Insulin resistance; Insulin secretion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Opipramol / Ansiolíticos / Islotes Pancreáticos Límite: Animals / Humans Idioma: En Revista: J Physiol Biochem Asunto de la revista: BIOQUIMICA / FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: España

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