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Steroidal alkaloids from the roots of Veratrum stenophyllum.
Zhou, Zhong-Shun; Liu, Yang-Yang; Zhu, Yan-Yan; Hu, Bin-Yuan; He, Ying-Jie; Luo, Xiao-Dong.
Afiliación
  • Zhou ZS; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China.
  • Liu YY; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China.
  • Zhu YY; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China.
  • Hu BY; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China.
  • He YJ; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China.
  • Luo XD; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China; State Key Laboratory of Phytochemistry and Plant Resources
Fitoterapia ; 166: 105464, 2023 Apr.
Article en En | MEDLINE | ID: mdl-36848963
ABSTRACT
Three new steroidal alkaloids, veratrasines A - C (1-3), along with ten known analogues (4-13) were isolated from the roots of Veratrum stenophyllum. Their structures were elucidated by NMR and HRESIMS data and comparison with the reported data in the literatures. A plausible biosynthetic pathway for 1 and 2 were proposed. Compounds 1, 3, and 8 showed moderate cytotoxic activity against MHCC97H and H1299 cell lines.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Veratrum / Alcaloides Idioma: En Revista: Fitoterapia Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Veratrum / Alcaloides Idioma: En Revista: Fitoterapia Año: 2023 Tipo del documento: Article