Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis.

Gao, Yanhua; Qian, Qi; Xun, Ge; Zhang, Jia; Sun, Shuo; Liu, Xin; Liu, Fangfang; Ge, Jiachen; Zhang, Huaxing; Fu, Yan; Su, Suwen; Wang, Xu; Wang, Qiao

Gao, Yanhua; Qian, Qi; Xun, Ge; Zhang, Jia; Sun, Shuo; Liu, Xin; Liu, Fangfang; Ge, Jiachen; Zhang, Huaxing; Fu, Yan; Su, Suwen; Wang, Xu; Wang, Qiao.

Afiliación

Gao Y; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Qian Q; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Xun G; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Zhang J; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Sun S; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Liu X; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Liu F; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Ge J; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Zhang H; Core Facilities and Centers, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Fu Y; Core Facilities and Centers, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Su S; Key Laboratory of Pharmacology and Toxicology for New Drugs, Department of Pharmacology, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Wang X; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.
Wang Q; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, People's Republic of China.

Comput Struct Biotechnol J ; 21: 1828-1842, 2023.

Article en En | MEDLINE | ID: mdl-36923473

Palabras clave

CDS, Calibrant Delivery System; CFA, Complete Freund's adjuvant; CIA, collagen-induced arthritis; CUR, curtain gas; DMARDs, disease-modifying anti-rheumatic drugs; ESI, electrospray ionization; FC, fold change; GS1, nebulizer gas; GS2, heater gas; HMDB, Human Metabolome Database; IDA, Information Dependent Acquisition; IgG, immunoglobulin G; Lipid metabolisms; Metabolomics; Micro-CT, Micro-computed tomography; Network analysis; QC, quality control; RA, rheumatoid arthritis; ROC, Receiver operating characteristic; Rheumatoid arthritis; TGT, Tripterygium glycosides tablets; Tripterygium glycosides tablets; VIP, variable importance in projection

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Comput Struct Biotechnol J Año: 2023 Tipo del documento: Article

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