Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high-grade serous ovarian cancer.

Deng, Feng; Laasik, Maren; Salminen, Liina; Lapatto, Lauri; Huhtinen, Kaisa; Li, Yilin; Hautaniemi, Sampsa; Hynninen, Johanna; Niemi, Mikko; Lehtonen, Rainer

Deng, Feng; Laasik, Maren; Salminen, Liina; Lapatto, Lauri; Huhtinen, Kaisa; Li, Yilin; Hautaniemi, Sampsa; Hynninen, Johanna; Niemi, Mikko; Lehtonen, Rainer.

Afiliación

Deng F; Department of Clinical Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Laasik M; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Salminen L; Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.
Lapatto L; Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.
Huhtinen K; Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Li Y; Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Hautaniemi S; Institute of Biomedicine and FICAN West Cancer Centre, Turku University Hospital and University of Turku, Turku, Finland.
Hynninen J; Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Niemi M; Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Lehtonen R; Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.

Basic Clin Pharmacol Toxicol ; 132(6): 521-531, 2023 Jun.

Article en En | MEDLINE | ID: mdl-36988399

Asunto(s)

Neoplasias Ováricas; Humanos; Femenino; Carboplatino/efectos adversos; Neoplasias Ováricas/tratamiento farmacológico; Neoplasias Ováricas/genética; Paclitaxel/efectos adversos; Polimorfismo de Nucleótido Simple; Genotipo; Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos; Gutatión-S-Transferasa pi/genética; Receptores Opioides mu/genética; Miembro 1B3 de la Familia de los Transportadores de Solutos de Aniones Orgánicos/genética; ADN Ligasa (ATP)/genética; Proteínas de Unión a Poli-ADP-Ribosa/genética

Palabras clave

chemotherapy; epithelial ovarian cancer; genetic association; therapy response; toxicity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Basic Clin Pharmacol Toxicol Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Finlandia

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