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The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.
Zhou, Jiechao; Wade, Sarah D; Graykowski, David; Xiao, Mei-Fang; Zhao, Binhui; Giannini, Lucia A A; Hanson, Jesse E; van Swieten, John C; Sheng, Morgan; Worley, Paul F; Dejanovic, Borislav.
Afiliación
  • Zhou J; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.
  • Wade SD; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
  • Graykowski D; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
  • Xiao MF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.
  • Zhao B; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
  • Giannini LAA; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands.
  • Hanson JE; Genentech, Neuroscience, South San Francisco, 94080, USA.
  • van Swieten JC; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands.
  • Sheng M; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
  • Worley PF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.
  • Dejanovic B; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.
Sci Transl Med ; 15(689): eadf0141, 2023 03 29.
Article en En | MEDLINE | ID: mdl-36989373
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microglía / Demencia Frontotemporal Límite: Aged / Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microglía / Demencia Frontotemporal Límite: Aged / Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos