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Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.
Lynch, Jason P; González-Prieto, Coral; Reeves, Analise Z; Bae, Sena; Powale, Urmila; Godbole, Neha P; Tremblay, Jacqueline M; Schmidt, Florian I; Ploegh, Hidde L; Kansra, Vikram; Glickman, Jonathan N; Leong, John M; Shoemaker, Charles B; Garrett, Wendy S; Lesser, Cammie F.
Afiliación
  • Lynch JP; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • González-Prieto C; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Reeves AZ; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Bae S; Departments of Immunology and Infectious Diseases and Harvard T.H. Chan Center for the Microbiome in Public Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • Powale U; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Godbole NP; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Tremblay JM; Department of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA.
  • Schmidt FI; Institute of Innate Immunity, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
  • Ploegh HL; Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Kansra V; Vicero Inc., Shrewsbury, MA 01545, USA.
  • Glickman JN; Department of Pathology, Massachusetts General Hospital, Boston, MA 02115, USA.
  • Leong JM; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA; Tufts Stuart B Levy Center for Integrated Management of Antimicrobial Resistance, Tufts University, Boston, MA 02111, USA.
  • Shoemaker CB; Department of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.
  • Garrett WS; Departments of Immunology and Infectious Diseases and Harvard T.H. Chan Center for the Microbiome in Public Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvar
  • Lesser CF; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142,
Cell Host Microbe ; 31(4): 634-649.e8, 2023 04 12.
Article en En | MEDLINE | ID: mdl-37003258
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colitis / Anticuerpos de Dominio Único Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colitis / Anticuerpos de Dominio Único Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos