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Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents.
Du, Chuanbiao; Yang, Xinlong; Long, Yan; Lang, Xueqing; Liu, Lige; Xu, Yajie; Wu, Hu; Chu, Yiwen; Hu, Xiaolei; Deng, Junfeng; Ji, Qinggang.
Afiliación
  • Du C; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Yang X; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Long Y; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Lang X; Key Laboratory of Laboratory Medicine Diagnostics, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
  • Liu L; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Xu Y; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Wu H; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
  • Chu Y; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, PR China.
  • Hu X; Key Laboratory of Laboratory Medicine Diagnostics, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: xiaolei_hu@cqmu.edu.cn.
  • Deng J; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, PR China. Electronic address: Dengjunfeng@cdu.edu.cn.
  • Ji Q; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address: jiqing@swu.edu.cn.
Eur J Med Chem ; 255: 115388, 2023 Jul 05.
Article en En | MEDLINE | ID: mdl-37141707
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quitina Sintasa / Antifúngicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quitina Sintasa / Antifúngicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article