Patients' perceptions on clinical trials outcomes in pulmonary arterial hypertension therapy.
Thorax
; 78(7): 721-725, 2023 07.
Article
en En
| MEDLINE
| ID: mdl-37142420
ABSTRACT
The value placed by patients and their caregivers on the components of composite outcomes in pulmonary arterial hypertension (PAH) remains unknown. We surveyed the importance of these outcomes from a patients' and caregivers' perspective, with participants (n=335, including 257 patients with PAH) rating individual components defining clinical worsening in PAH trials as of critical, major, mild-to-moderate or minor importance. Most outcomes were considered of major or mild-to-moderate importance to patients. Death was the only outcome considered of critical importance. Perceptions of clinical outcomes varied between patients and caregivers. Integrating patients' perception in the elaboration of clinical trials is essential.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hipertensión Arterial Pulmonar
Límite:
Humans
Idioma:
En
Revista:
Thorax
Año:
2023
Tipo del documento:
Article
País de afiliación:
Canadá