Stimulation of antitumor immunity by FoxP3-targeting PROTAC.

Wang, Yanping; Zhang, Yi; Su, Shengchen; Tamukong, Patrick; Murali, Ramachandran; Kim, Hyung L

Wang, Yanping; Zhang, Yi; Su, Shengchen; Tamukong, Patrick; Murali, Ramachandran; Kim, Hyung L.

Afiliación

Wang Y; Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States of America.
Zhang Y; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA, United States of America.
Su S; Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States of America.
Tamukong P; Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States of America.
Murali R; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA, United States of America; Research Division of Immunology, Cedars Sinai Medical Center, Los Angeles, CA, United States of America.
Kim HL; Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States of America. Electronic address: kimhl@cshs.org.

Biomed Pharmacother ; 163: 114871, 2023 Jul.

Article en En | MEDLINE | ID: mdl-37182514

Asunto(s)

Neoplasias; Linfocitos T Reguladores; Animales; Humanos; Ratones; Factores de Transcripción Forkhead/metabolismo; Activación de Linfocitos; Neoplasias/tratamiento farmacológico; Neoplasias/metabolismo; Proteolisis; Factores de Transcripción/metabolismo; Quimera Dirigida a la Proteólisis/química; Quimera Dirigida a la Proteólisis/farmacología

Palabras clave

Checkpoint inhibitor; Immunotherapy; MTOR inhibitor; Tregs

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Neoplasias Límite: Animals / Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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