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Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
Chen, Wenqiang; Huang, Qian; Lazdon, Ekaterina Katie; Gomes, Antonio; Wong, Marisa; Stephens, Emily; Royal, Tabitha Grace; Frenkel, Dan; Cai, Weikang; Kahn, C Ronald.
Afiliación
  • Chen W; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA 02215.
  • Huang Q; Department of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY 11568.
  • Lazdon EK; Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
  • Gomes A; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA 02215.
  • Wong M; Department of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY 11568.
  • Stephens E; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA 02215.
  • Royal TG; School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430.
  • Frenkel D; Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
  • Cai W; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
  • Kahn CR; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 120(21): e2220684120, 2023 05 23.
Article en En | MEDLINE | ID: mdl-37186836

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article