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Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers.
Joo, Jihoon E; Mahmood, Khalid; Walker, Romy; Georgeson, Peter; Candiloro, Ida; Clendenning, Mark; Como, Julia; Joseland, Sharelle; Preston, Susan; Graversen, Lise; Wilding, Mathilda; Field, Michael; Lemon, Michelle; Wakeling, Janette; Marfan, Helen; Susman, Rachel; Isbister, Joanne; Edwards, Emma; Bowman, Michelle; Kirk, Judy; Ip, Emilia; McKay, Lynne; Antill, Yoland; Hopper, John L; Boussioutas, Alex; Macrae, Finlay A; Dobrovic, Alexander; Jenkins, Mark A; Rosty, Christophe; Winship, Ingrid M; Buchanan, Daniel D.
Afiliación
  • Joo JE; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia. ji.joo@unimelb.edu.au.
  • Mahmood K; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia. ji.joo@unimelb.edu.au.
  • Walker R; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Georgeson P; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Candiloro I; Melbourne Bioinformatics, The University of Melbourne, Melbourne, VIC, Australia.
  • Clendenning M; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Como J; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Joseland S; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Preston S; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Graversen L; Beacon Biomarkers Lab, Department of Surgery, Austin Health, University of Melbourne, Heidelberg, VIC, Australia.
  • Wilding M; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Field M; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Lemon M; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Wakeling J; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Marfan H; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Susman R; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Isbister J; Colorectal Oncogenomics Group, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, 305 Grattan Street, Parkville, VIC, 3000, Australia.
  • Edwards E; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, VIC, Australia.
  • Bowman M; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
  • Kirk J; Department of Clinical Genetics, Royal North Shore Hospital, Sydney, NSW, Australia.
  • Ip E; Department of Clinical Genetics, Royal North Shore Hospital, Sydney, NSW, Australia.
  • McKay L; Genetic Health Queensland, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
  • Antill Y; Genetic Health Queensland, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
  • Hopper JL; Tasman Health Care, Southport, QLD, Australia.
  • Boussioutas A; Genetic Health Queensland, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
  • Macrae FA; Genetic Health Queensland, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
  • Dobrovic A; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, Melbourne, VIC, Australia.
  • Jenkins MA; Familial Cancer Service, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, NSW, 2145, Australia.
  • Rosty C; Familial Cancer Service, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, NSW, 2145, Australia.
  • Winship IM; Familial Cancer Service, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, NSW, 2145, Australia.
  • Buchanan DD; Department of Cancer Genetics, Liverpool Hospital, Liverpool, NSW, Australia.
Clin Epigenetics ; 15(1): 95, 2023 06 03.
Article en En | MEDLINE | ID: mdl-37270516
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Neoplasias Colorrectales Hereditarias sin Poliposis Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Epigenetics Año: 2023 Tipo del documento: Article País de afiliación: Australia
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Neoplasias Colorrectales Hereditarias sin Poliposis Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Epigenetics Año: 2023 Tipo del documento: Article País de afiliación: Australia