Natural Cyclophilin A Inhibitors Suppress the Growth of Cancer Stem Cells in Non-Small Cell Lung Cancer by Disrupting Crosstalk between CypA/CD147 and EGFR.

Han, Jang Mi; Kim, Sung Min; Kim, Hong Lae; Cho, Hee Jeong; Jung, Hye Jin

Han, Jang Mi; Kim, Sung Min; Kim, Hong Lae; Cho, Hee Jeong; Jung, Hye Jin.

Afiliación

Han JM; Department of Life Science and Biochemical Engineering, Graduate School, Sun Moon University, Asan 31460, Republic of Korea.
Kim SM; Department of Life Science and Biochemical Engineering, Graduate School, Sun Moon University, Asan 31460, Republic of Korea.
Kim HL; Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University, Asan 31460, Republic of Korea.
Cho HJ; Department of Life Science and Biochemical Engineering, Graduate School, Sun Moon University, Asan 31460, Republic of Korea.
Jung HJ; Department of Life Science and Biochemical Engineering, Graduate School, Sun Moon University, Asan 31460, Republic of Korea.

Int J Mol Sci ; 24(11)2023 May 29.

Article en En | MEDLINE | ID: mdl-37298389

Asunto(s)

Antineoplásicos; Carcinoma de Pulmón de Células no Pequeñas; Neoplasias Pulmonares; Humanos; Carcinoma de Pulmón de Células no Pequeñas/patología; Ciclofilina A/genética; Ciclofilina A/metabolismo; Afatinib/farmacología; Neoplasias Pulmonares/metabolismo; Línea Celular Tumoral; Receptores ErbB/metabolismo; Antineoplásicos/farmacología; Células Madre Neoplásicas/metabolismo

Palabras clave

CD147; afatinib; cancer stem cell; compound 9; cyclophilin A; cyclosporin A; epidermal growth factor receptor; non-small cell lung cancer

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares / Antineoplásicos Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article

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