Designing the 5HT<sub>2B</sub>R structure and its modulation as a therapeutic target for repurposing approach in drug-resistant epilepsy.

Chauhan, Arushi; Singh, Jitender; Sangwan, Namrata; Singh, Harvinder; Prakash, Ajay; Medhi, Bikash; Avti, Pramod K

Designing the 5HT_2BR structure and its modulation as a therapeutic target for repurposing approach in drug-resistant epilepsy.

Chauhan, Arushi; Singh, Jitender; Sangwan, Namrata; Singh, Harvinder; Prakash, Ajay; Medhi, Bikash; Avti, Pramod K.

Afiliación

Chauhan A; Department of Biophysics, PGIMER, Chandigarh, India.
Singh J; Department of Biophysics, PGIMER, Chandigarh, India.
Sangwan N; Department of Biophysics, PGIMER, Chandigarh, India.
Singh H; Department of Pharmacology, PGIMER, Chandigarh, India.
Prakash A; Department of Pharmacology, PGIMER, Chandigarh, India.
Medhi B; Department of Pharmacology, PGIMER, Chandigarh, India.
Avti PK; Department of Biophysics, PGIMER, Chandigarh, India. Electronic address: pramod.avti@gmail.com.

Epilepsy Res ; 194: 107168, 2023 08.

Article en En | MEDLINE | ID: mdl-37302343

Asunto(s)

Epilepsia; Metilergonovina; Humanos; Cabergolina; Reposicionamiento de Medicamentos; Simulación de Dinámica Molecular

Palabras clave

5HT(2B)R; Drug-resistant epilepsy (DRE); Molecular Dynamics Simulations (MD); Radius of gyration (R(Gyr)); Serotonin receptors

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Epilepsia / Metilergonovina Límite: Humans Idioma: En Revista: Epilepsy Res Asunto de la revista: CEREBRO / NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: India

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