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Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV.
Chang, Yu-Jen; Le, Uyen Nguyen Phuong; Liu, Jia-Jun; Li, Sin-Rong; Chao, Shao-Ting; Lai, Hsueh-Chou; Lin, Yu-Feng; Hsu, Kai-Cheng; Lu, Chih-Hao; Lin, Cheng-Wen.
Afiliación
  • Chang YJ; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan.
  • Le UNP; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan; Graduate Institute of Biological Sciences and Technology, China Medical University, Taichung, Taiwan.
  • Liu JJ; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
  • Li SR; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan; Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Chao ST; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.
  • Lai HC; Division of Hepato-Gastroenterology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Lin YF; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.
  • Hsu KC; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan.
  • Lu CH; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Department of Biological Science and Technology, National Yang Ming Chiao Tung Universit
  • Lin CW; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan; Graduate Institute of Biological Sciences and Technology, China Medical University, Taichung
Antiviral Res ; 216: 105653, 2023 08.
Article en En | MEDLINE | ID: mdl-37321487
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Coronavirus del Síndrome Respiratorio de Oriente Medio / COVID-19 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Antiviral Res Año: 2023 Tipo del documento: Article País de afiliación: Taiwán
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Coronavirus del Síndrome Respiratorio de Oriente Medio / COVID-19 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Antiviral Res Año: 2023 Tipo del documento: Article País de afiliación: Taiwán