Predicting mechanisms of action at genetic loci associated with discordant effects on type 2 diabetes and abdominal fat accumulation.

Aberra, Yonathan Tamrat; Ma, Lijiang; Björkegren, Johan L M; Civelek, Mete

Aberra, Yonathan Tamrat; Ma, Lijiang; Björkegren, Johan L M; Civelek, Mete.

Afiliación

Aberra YT; Department of Biomedical Engineering, University of Virginia, Charlottesville, United States.
Ma L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States.
Björkegren JLM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States.
Civelek M; Department of Biomedical Engineering, University of Virginia, Charlottesville, United States.

Elife ; 122023 Jun 16.

Article en En | MEDLINE | ID: mdl-37326626

Asunto(s)

Diabetes Mellitus Tipo 2; Humanos; Diabetes Mellitus Tipo 2/genética; Diabetes Mellitus Tipo 2/complicaciones; Obesidad Abdominal/genética; Obesidad Abdominal/complicaciones; Estudio de Asociación del Genoma Completo; Obesidad/genética; Obesidad/complicaciones; Sitios Genéticos; Grasa Abdominal

Palabras clave

body fat distribution; computational biology; functional genomics; human; metabolically healthy obesity; statistical genetics; systems biology; type 2 diabetes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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