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Clinical symptoms of SARS-CoV-2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination-A prospective multicentre cohort of health professionals (SURPRISE study).
Kohler, Philipp; Babouee Flury, Baharak; Güsewell, Sabine; Egger, Thomas; Leal, Onicio; Brucher, Angela; Lemmenmeier, Eva; Meier Kleeb, Dorette; Möller, J Carsten; Ortner, Manuela; Rieder, Philip; Ruetti, Markus; Schmid, Hans-Ruedi; Stocker, Reto; Vuichard-Gysin, Danielle; Speer, Oliver; Wiggli, Benedikt; Besold, Ulrike; McGeer, Allison; Risch, Lorenz; Friedl, Andrée; Schlegel, Matthias; Vernazza, Pietro; Kahlert, Christian R; Kuster, Stefan P.
Afiliación
  • Kohler P; Division of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
  • Babouee Flury B; Division of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
  • Güsewell S; Division of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
  • Egger T; Division of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
  • Leal O; Epitrack Recife Brazil.
  • Brucher A; Department of Economics University of Zurich Zurich Switzerland.
  • Lemmenmeier E; Psychiatry Services of the Canton of St. Gallen (South) Pfäfers Switzerland.
  • Meier Kleeb D; Clienia Littenheid AG, Private Clinic for Psychiatry and Psychotherapy Littenheid Switzerland.
  • Möller JC; Division of Occupational Health Kantonsspital Baden Baden Switzerland.
  • Ortner M; Center for Neurological Rehabilitation Zihlschlacht Switzerland.
  • Rieder P; Rheintal Werdenberg Sarganserland Hospital Group Grabs Switzerland.
  • Ruetti M; Hirslanden Clinic Zurich Switzerland.
  • Schmid HR; Fuerstenland Toggenburg Hospital Group Wil Switzerland.
  • Stocker R; Kantonsspital Baden, Central Laboratory Baden Switzerland.
  • Vuichard-Gysin D; Hirslanden Clinic Zurich Switzerland.
  • Speer O; Division of Infectious Diseases and Hospital Epidemiology Thurgau Hospital Group Muensterlingen Switzerland.
  • Wiggli B; Thurgau Hospital Group Institute for Laboratory Medicine Muensterlingen Switzerland.
  • Besold U; Division of Infectious Diseases and Hospital Epidemiology Kantonsspital Baden Baden Switzerland.
  • McGeer A; Geriatric Clinic St. Gallen St. Gallen Switzerland.
  • Risch L; Sinai Health System Toronto Canada.
  • Friedl A; Labormedizinisches Zentrum Dr Risch Ostschweiz AG Buchs Switzerland.
  • Schlegel M; Private Universität im Fürstentum Liechtenstein Triesen Liechtenstein.
  • Vernazza P; Center of Laboratory Medicine University Institute of Clinical Chemistry, University of Bern, Inselspital Bern Switzerland.
  • Kahlert CR; Thurgau Hospital Group Institute for Laboratory Medicine Muensterlingen Switzerland.
  • Kuster SP; Division of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Influenza Other Respir Viruses ; 17(6): e13167, 2023 Jun.
Article en En | MEDLINE | ID: mdl-37346094
ABSTRACT
The effects of different types of pre-existing immunity on the frequency of clinical symptoms caused by the SARS-CoV-2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for dizziness, muscle or limb pain and headache as compared to vaccination only. Moreover, the frequencies of dizziness, cough and muscle or limb pain were lower in participants who had received a booster vaccine dose. Thus, hybrid immunity appeared to be superior in preventing specific symptoms during breakthrough infection compared to vaccination alone. A booster vaccine dose conferred additional symptom reduction.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas / COVID-19 Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Influenza Other Respir Viruses Asunto de la revista: VIROLOGIA Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas / COVID-19 Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Influenza Other Respir Viruses Asunto de la revista: VIROLOGIA Año: 2023 Tipo del documento: Article