Geographic distribution of United States clinical trial sites utilized for guideline changing studies of cholesterol management.
Am Heart J
; 264: 174-176, 2023 10.
Article
en En
| MEDLINE
| ID: mdl-37379956
ABSTRACT
BACKGROUND:
This study aimed to evaluate the geographic distribution of United States (US) clinical trial sites utilizedfor guideline changing studies of cholesterol management.METHODS:
Randomized trials evaluating pharmacologic interventions for cholesterol treatment and reporting location data (ie, zip code of trial sites) were identified. Location data was abstracted from ClinicalTrials.gov.RESULTS:
Half of US counties were over 30 miles from a study site and, social determinants of health were more favorable in counties with versus without clinical trial sites.CONCLUSIONS:
Stakeholders such as regulatory bodies andtrial sponsors should incentivize and support infrastructure that would enable a larger number of US counties to be utilized for clinical trial sites. TRIAL REGISTRATION Not applicable.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hipercolesterolemia
Tipo de estudio:
Clinical_trials
/
Guideline
/
Prognostic_studies
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Am Heart J
Año:
2023
Tipo del documento:
Article
País de afiliación:
Arabia Saudita