Levels of nasal nitric oxide and nitric oxide synthase expression in chronic rhinosinusitis with nasal polyposis.

Wu, Vincent; Cusimano, Michael; Marsden, Philip; Lee, John M

Wu, Vincent; Cusimano, Michael; Marsden, Philip; Lee, John M.

Afiliación

Wu V; Division of Rhinology, Department of Otolaryngology - Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Canada.
Cusimano M; Division of Neurosurgery, Department of Surgery, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Canada.
Marsden P; Keenan Research Centre, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Lee JM; Division of Rhinology, Department of Otolaryngology - Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Canada.

Int Forum Allergy Rhinol ; 14(1): 127-129, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37395064

RESUMEN

KEY POINTS: CRSwNP patients had decreased nNO and increased SNOT-22, endoscopy, and CT scores. CRSwNP patients exhibited decreased nNO despite elevated iNOS and eNOS mRNA expression. The mechanism behind lowered nNO in CRSwNP may not be related to NOS expression.

Asunto(s)

Pólipos Nasales; Rinitis; Rinosinusitis; Sinusitis; Humanos; Rinitis/patología; Óxido Nítrico/metabolismo; Sinusitis/patología; Pólipos Nasales/patología; Mucosa Nasal/patología; Enfermedad Crónica

Palabras clave

CRSwNP; chronic rhinosinusitis; nitric oxide

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sinusitis / Rinitis / Pólipos Nasales / Rinosinusitis Límite: Humans Idioma: En Revista: Int Forum Allergy Rhinol Año: 2024 Tipo del documento: Article País de afiliación: Canadá

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