A validated capillary microsampling liquid chromatography-tandem mass spectrometry method for quantification of antisense oligonucleotides in mouse serum.

Yuan, Long; Dupuis, Jean-François; Vrionis, Valerie; Mekhssian, Kevork; Magee, Tom

Yuan, Long; Dupuis, Jean-François; Vrionis, Valerie; Mekhssian, Kevork; Magee, Tom.

Afiliación

Yuan L; Drug Metabolism & Pharmacokinetics, Biogen, 225 Binney St., Cambridge, MA 02142, USA.
Dupuis JF; Altasciences, 575 Armand-Frappier Blvd, Laval, QC, H7V 4B3, Canada.
Vrionis V; Altasciences, 575 Armand-Frappier Blvd, Laval, QC, H7V 4B3, Canada.
Mekhssian K; Altasciences, 575 Armand-Frappier Blvd, Laval, QC, H7V 4B3, Canada.
Magee T; Preclinical Safety, Biogen, 225 Binney St., Cambridge, MA 02142, USA.

Bioanalysis ; 15(12): 683-694, 2023 Jun.

Article en En | MEDLINE | ID: mdl-37408387

Palabras clave

CMS; LCMS/MS; antisense oligonucleotides; capillary microsampling (CMS); hybridization; microsampling; quantitative bioanalysis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Bioanalysis Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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