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Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52.
Stirm, Michael; Shashikadze, Bachuki; Blutke, Andreas; Kemter, Elisabeth; Lange, Andreas; Stöckl, Jan B; Jaudas, Florian; Laane, Laeticia; Kurome, Mayuko; Keßler, Barbara; Zakhartchenko, Valeri; Bähr, Andrea; Klymiuk, Nikolai; Nagashima, Hiroshi; Walter, Maggie C; Wurst, Wolfgang; Kupatt, Christian; Fröhlich, Thomas; Wolf, Eckhard.
Afiliación
  • Stirm M; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Shashikadze B; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Blutke A; Laboratory for Functional Genome Analysis, Gene Center, LMU Munich, Munich 81377, Germany.
  • Kemter E; Institute of Veterinary Pathology, Center for Clinical Veterinary Medicine, LMU Munich, Munich 80539, Germany.
  • Lange A; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Stöckl JB; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Jaudas F; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Laane L; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Kurome M; Laboratory for Functional Genome Analysis, Gene Center, LMU Munich, Munich 81377, Germany.
  • Keßler B; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Zakhartchenko V; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Bähr A; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Klymiuk N; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Nagashima H; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Walter MC; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Wurst W; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Kupatt C; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
  • Fröhlich T; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich 81377, Germany.
  • Wolf E; Center for Innovative Medical Models, Department of Veterinary Sciences, LMU Munich, Oberschleissheim 85764, Germany.
Proc Natl Acad Sci U S A ; 120(29): e2301250120, 2023 07 18.
Article en En | MEDLINE | ID: mdl-37428903
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Alemania