Your browser doesn't support javascript.
loading
Insight into contact force local impedance technology for predicting effective pulmonary vein isolation.
Lepillier, Antoine; Maggio, Ruggero; De Sanctis, Valerio; Malacrida, Maurizio; Stabile, Giuseppe; Zakine, Cyril; Champ-Rigot, Laure; Anselmino, Matteo; Segreti, Luca; Dell'Era, Gabriele; Garnier, Fabien; Mascia, Giuseppe; Pandozi, Claudio; Dello Russo, Antonio; Scaglione, Marco; Cosaro, Giuseppe; Ferraro, Anna; Paziaud, Olivier; Maglia, Giampiero; Solimene, Francesco.
Afiliación
  • Lepillier A; Centre Cardiologique du Nord, Saint-Denis, France.
  • Maggio R; Infermi Hospital, Rivoli, Italy.
  • De Sanctis V; IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
  • Malacrida M; Boston Scientific, Milan, Italy.
  • Stabile G; Mediterranea Cardiocentro, Napoli, Italy.
  • Zakine C; Clinique NCT, St Cyr sur Loire, France.
  • Champ-Rigot L; Normandie Univ, UNICAEN, CHU de Caen Normandie, Caen, France.
  • Anselmino M; Division of Cardiology, "Città della Salute e della Scienza di Torino" Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
  • Segreti L; Second Division of Cardiology, Cardiac-Thoracic-Vascular Department, New Santa Chiara Hospital, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
  • Dell'Era G; Azienda Ospedaliera Universitaria "Maggiore della Carità", Novara, Italy.
  • Garnier F; Centre Hospitalier de Dijon Bourgogne, Dijon, France.
  • Mascia G; IRCCS San Martino Polyclinic Hospital, Genoa, Italy.
  • Pandozi C; San Filippo Neri Hospital, Roma, Italy.
  • Dello Russo A; Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Ancona, Italy.
  • Scaglione M; Cardinal Massaia Hospital, Asti, Italy.
  • Cosaro G; Boston Scientific, Milan, Italy.
  • Ferraro A; Infermi Hospital, Rivoli, Italy.
  • Paziaud O; Centre Cardiologique du Nord, Saint-Denis, France.
  • Maglia G; Azienda Ospedaliera Pugliese Ciaccio, Catanzaro, Italy.
  • Solimene F; Department of Cardiac Electrophysiology and Arrhythmology, Clinica Montevergine, Mercogliano, Italy.
Front Cardiovasc Med ; 10: 1169037, 2023.
Article en En | MEDLINE | ID: mdl-37476572
Background: Highly localized impedance (LI) measurements during atrial fibrillation (AF) ablation have the potential to act as a reliable predictor of the durability of the lesions created. Objective: We aimed to collect data on the procedural parameters affecting LI-guided ablation in a large multicenter registry. Methods: A total of 212 consecutive patients enrolled in the CHARISMA registry and undergoing their first pulmonary vein (PV) isolation for paroxysmal and persistent AF were included. Results: In all, 13,891 radiofrequency (RF) applications of ≥3 s duration were assessed. The first-pass PV isolation rate was 93.3%. A total of 80 PV gaps were detected. At successful ablation spots, baseline LI and absolute LI drop were larger than at PV gap spots (161.4 ± 19â€…Ω vs. 153.0 ± 13 Ω, p < 0.0001 for baseline LI; 22.1 ± 9â€…Ω vs. 14.4 ± 5 Ω, p < 0.0001 for LI drop). On the basis of Receiver operating characteristic curve analysis, the ideal LI drop, which predicted successful ablation, was >21â€…Ω at anterior sites and >18â€…Ω at posterior sites. There was a non-linear association between the magnitude of LI drop and contact-force (CF) (r = 0.14, 95% CI: 0.13-0.16, p < 0.0001) whereas both CF and LI drop were inversely related with delivery time (DT) (-0.22, -0.23 to -0.20, p < 0.0001 for CF; -0.27, -0.29 to -0.26, p < 0.0001 for LI drop). Conclusion: An LI drop >21â€…Ω at anterior sites and >18â€…Ω at posterior sites predicts successful ablation. A higher CF was associated with an increased likelihood of ideal LI drop. The combination of good CF and adequate LI drop allows a significant reduction in RF DT. Clinical trial registration: http://clinicaltrials.gov/, identifier: NCT03793998.
Palabras clave

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Cardiovasc Med Año: 2023 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Cardiovasc Med Año: 2023 Tipo del documento: Article País de afiliación: Francia