Identification of an adverse outcome pathway (AOP) for chemical-induced craniofacial anomalies using the transgenic zebrafish model.

Liu, Shujie; Kawanishi, Toru; Shimada, Atsuko; Ikeda, Naohiro; Yamane, Masayuki; Takeda, Hiroyuki; Tasaki, Junichi

Liu, Shujie; Kawanishi, Toru; Shimada, Atsuko; Ikeda, Naohiro; Yamane, Masayuki; Takeda, Hiroyuki; Tasaki, Junichi.

Afiliación

Liu S; R&D, Safety Science Research, Kao Corporation, Tochigi 321-3497, Japan.
Kawanishi T; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.
Shimada A; School of Life Science and Technology, Tokyo Institute of Technology, Kanagawa 226-8501, Japan.
Ikeda N; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.
Yamane M; R&D, Safety Science Research, Kao Corporation, Kanagawa 210-0821, Japan.
Takeda H; R&D, Safety Science Research, Kao Corporation, Tochigi 321-3497, Japan.
Tasaki J; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.

Toxicol Sci ; 196(1): 38-51, 2023 10 30.

Article en En | MEDLINE | ID: mdl-37531284

Asunto(s)

Rutas de Resultados Adversos; Pez Cebra; Animales; Humanos; Pez Cebra/genética; Pez Cebra/metabolismo; Cráneo; Regulación del Desarrollo de la Expresión Génica; Teratógenos/farmacología; Mamíferos

Palabras clave

adverse outcome pathway (AOP); cranial neural crest cells; craniofacial anomalies; teratogen; transgenic zebrafish model

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pez Cebra / Rutas de Resultados Adversos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Japón

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