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Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.
Hudaiberdiev, Sanjarbek; Taylor, D Leland; Song, Wei; Narisu, Narisu; Bhuiyan, Redwan M; Taylor, Henry J; Tang, Xuming; Yan, Tingfen; Swift, Amy J; Bonnycastle, Lori L; Consortium, Diamante; Chen, Shuibing; Stitzel, Michael L; Erdos, Michael R; Ovcharenko, Ivan; Collins, Francis S.
Afiliación
  • Hudaiberdiev S; Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20892.
  • Taylor DL; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Song W; Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20892.
  • Narisu N; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Bhuiyan RM; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032.
  • Taylor HJ; Department of Genetics and Genome Sciences, University of Connecticut, Farmington, CT 06032.
  • Tang X; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Yan T; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
  • Swift AJ; Department of Surgery, Weill Cornell Medicine, New York, NY 10065.
  • Bonnycastle LL; Center for Genomic Health, Weill Cornell Medicine, New York, NY 10065.
  • Consortium D; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Chen S; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Stitzel ML; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.
  • Ovcharenko I; Department of Surgery, Weill Cornell Medicine, New York, NY 10065.
  • Collins FS; Center for Genomic Health, Weill Cornell Medicine, New York, NY 10065.
Proc Natl Acad Sci U S A ; 120(35): e2206612120, 2023 08 29.
Article en En | MEDLINE | ID: mdl-37603758
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Elementos de Facilitación Genéticos / Diabetes Mellitus Tipo 2 / Aprendizaje Profundo Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Elementos de Facilitación Genéticos / Diabetes Mellitus Tipo 2 / Aprendizaje Profundo Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article