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Absorption, Metabolism, and Excretion of [14C]-Tolebrutinib After Oral Administration in Humans, Contribution of the Metabolites to Pharmacological Activity.
Nicolas, Olivier; Moliner, Patricia; Soubayrol, Patrick; Vitse, Olivier; Roy, Sebastien; Cabanis, Marie-José; Turner, Tim; Klieber, Sylvie; Muccio, Stephane; Arabeyre, Catherine; Brun, Priscilla.
Afiliación
  • Nicolas O; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France. Olivier.Nicolas@sanofi.com.
  • Moliner P; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Soubayrol P; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Vitse O; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Roy S; Department of Integrated Drug Discovery/Isotope Chemistry, Sanofi, Paris, France.
  • Cabanis MJ; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Turner T; MS Neurology Development, Sanofi, Cambridge, MA, USA.
  • Klieber S; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Muccio S; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Arabeyre C; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
  • Brun P; Department of Translational Medicine and Early Development, Sanofi, 371 Rue Professeur Blayac, 34184, Montpellier, France.
Clin Drug Investig ; 43(8): 653-665, 2023 Aug.
Article en En | MEDLINE | ID: mdl-37642857
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas Límite: Humans / Male Idioma: En Revista: Clin Drug Investig Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas Límite: Humans / Male Idioma: En Revista: Clin Drug Investig Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Francia