Structural Mechanism and Inhibitors Targeting EGFR Exon 20 Insertion (Ex20ins) Mutations.

Chen, Hao; Hu, Shiliang; Patterson, Adam V; Smaill, Jeff B; Ding, Ke; Lu, Xiaoyun

Chen, Hao; Hu, Shiliang; Patterson, Adam V; Smaill, Jeff B; Ding, Ke; Lu, Xiaoyun.

Afiliación

Chen H; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou 510632, China.
Hu S; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou 510632, China.
Patterson AV; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Smaill JB; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Ding K; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Lu X; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.

J Med Chem ; 66(17): 11656-11671, 2023 09 14.

Article en En | MEDLINE | ID: mdl-37669428

Asunto(s)

Receptores ErbB; Neoplasias Pulmonares; Humanos; Receptores ErbB/genética; Exones; Mutación

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores ErbB / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China

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