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A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection.
Narayanan, S Anand; Jamison, David A; Guarnieri, Joseph W; Zaksas, Victoria; Topper, Michael; Koutnik, Andrew P; Park, Jiwoon; Clark, Kevin B; Enguita, Francisco J; Leitão, Ana Lúcia; Das, Saswati; Moraes-Vieira, Pedro M; Galeano, Diego; Mason, Christopher E; Trovão, Nídia S; Schwartz, Robert E; Schisler, Jonathan C; Coelho-Dos-Reis, Jordana G A; Wurtele, Eve Syrkin; Beheshti, Afshin.
Afiliación
  • Narayanan SA; COVID-19 International Research Team, Medford, MA, 02155, USA. anarayan09@gmail.com.
  • Jamison DA; Department of Health, Nutrition and Food Sciences, Florida State University, Tallahassee, FL, 32301, USA. anarayan09@gmail.com.
  • Guarnieri JW; COVID-19 International Research Team, Medford, MA, 02155, USA.
  • Zaksas V; COVID-19 International Research Team, Medford, MA, 02155, USA.
  • Topper M; Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Koutnik AP; COVID-19 International Research Team, Medford, MA, 02155, USA.
  • Park J; Center for Translational Data Science, University of Chicago, Chicago, IL, 60637, USA.
  • Clark KB; Clever Research Lab, Springfield, IL, 62704, USA.
  • Enguita FJ; COVID-19 International Research Team, Medford, MA, 02155, USA.
  • Leitão AL; Departments of Oncology and Medicine and the Sidney Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
  • Das S; Human Healthspan, Resilience, and Performance, Florida Institute for Human and Machine Cognition, Pensacola, FL, 32502, USA.
  • Moraes-Vieira PM; Sansum Diabetes Research Institute, Santa Barbara, CA, 93015, USA.
  • Galeano D; Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, USA.
  • Mason CE; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, 10065, USA.
  • Trovão NS; COVID-19 International Research Team, Medford, MA, 02155, USA.
  • Schwartz RE; Cures Within Reach, Chicago, IL, 60602, USA.
  • Schisler JC; Campus and Domain Champions Program, Multi-Tier Assistance, Training, and Computational Help (MATCH) Track, National Science Foundation's Advanced Cyberinfrastructure Coordination Ecosystem: Services and Support (ACCESS), Philadelphia, PA, USA.
  • Coelho-Dos-Reis JGA; Expert Network, Penn Center for Innovation, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Wurtele ES; Biometrics and Nanotechnology Councils, Institute for Electrical and Electronics Engineers, New York, NY, 10016, USA.
  • Beheshti A; Peace Innovation Institute, The Hague 2511, Netherlands and Stanford University, Palo Alto, 94305, CA, USA.
Eur J Hum Genet ; 32(1): 10-20, 2024 Jan.
Article en En | MEDLINE | ID: mdl-37938797
ABSTRACT
COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and mortality worldwide. The betacoronavirus continues to evolve with global health implications as we race to learn more to curb its transmission, evolution, and sequelae. The focus of this review, the second of a three-part series, is on the biological effects of the SARS-CoV-2 virus on post-acute disease in the context of tissue and organ adaptations and damage. We highlight the current knowledge and describe how virological, animal, and clinical studies have shed light on the mechanisms driving the varied clinical diagnoses and observations of COVID-19 patients. Moreover, we describe how investigations into SARS-CoV-2 effects have informed the understanding of viral pathogenesis and provide innovative pathways for future research on the mechanisms of viral diseases.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: COVID-19 Límite: Animals / Humans Idioma: En Revista: Eur J Hum Genet Asunto de la revista: GENETICA MEDICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: COVID-19 Límite: Animals / Humans Idioma: En Revista: Eur J Hum Genet Asunto de la revista: GENETICA MEDICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos