Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.

Huang, Yige; Liu, Bangyan; Sinha, Subhash C; Amin, Sadaf; Gan, Li

Huang, Yige; Liu, Bangyan; Sinha, Subhash C; Amin, Sadaf; Gan, Li.

Afiliación

Huang Y; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Liu B; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.
Sinha SC; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Amin S; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.
Gan L; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.

Mol Neurodegener ; 18(1): 79, 2023 Nov 08.

Article en En | MEDLINE | ID: mdl-37941028

Asunto(s)

Interferón Tipo I; Enfermedades del Sistema Nervioso; Humanos; Transducción de Señal/fisiología; Nucleotidiltransferasas/genética; Nucleotidiltransferasas/metabolismo; ADN/metabolismo; Interferón Tipo I/genética; Interferón Tipo I/metabolismo

Palabras clave

ALS; Alzheimer disease; Antiviral; Cytosolic dsDNA; Interferon response; Neuroinflammation; Parkinson disease; STING; cGAS

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Interferón Tipo I / Enfermedades del Sistema Nervioso Límite: Humans Idioma: En Revista: Mol Neurodegener Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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