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Adalimumab Drug Levels at Secondary Loss of Response Do Not Predict Response to Dose-intensification in Crohn's Disease: A Retrospective, International Multicenter Study.
Little, Robert D; Swaine, Adrian; Reynolds, Rebecca; Gibson, David J; Barrau, Mathilde; D'Errico, Francesca; Hampal, Rumneek; Sparrow, Miles P; Roblin, Xavier; Irving, Peter M; Ward, Mark G.
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  • Little RD; Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Australia.
  • Swaine A; Department of Gastroenterology, Redcliffe Hospital, Redcliffe, Australia.
  • Reynolds R; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
  • Gibson DJ; Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Australia.
  • Barrau M; Gastro-entérologie et Hépatologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
  • D'Errico F; Department of Gastroenterology and Endoscopy, Miulli Hospital, Acquaviva delle Fonti, Italy.
  • Hampal R; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
  • Sparrow MP; Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Australia.
  • Roblin X; Gastro-entérologie et Hépatologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
  • Irving PM; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
  • Ward MG; Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Australia.
Inflamm Bowel Dis ; 2023 Nov 10.
Article en En | MEDLINE | ID: mdl-37951220
Literature supporting therapeutic drug monitoring at secondary loss of response and post dose-intensification of adalimumab is limited. Adalimumab drug levels following dose-intensification rather than at the time of secondary loss of response are associated with subsequent Crohn's disease remission.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Australia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Australia