Alkali-Driven Photoinduced N-Dealkylation of Aryl Tertiary Amines and Amides.
Org Lett
; 25(46): 8387-8392, 2023 Nov 24.
Article
en En
| MEDLINE
| ID: mdl-37966124
ABSTRACT
By extending the photoinduced oxidative mechanism of aryl tertiary amines proposed earlier to an alkaline environment based on the prediction of quantum mechanics computations and the validation of meticulous experiments, we discovered a photoinduced oxidative N-dealkylation method for both aryl tertiary amines and amides. The dealkylation was achieved in an alkaline environment under mild conditions accompanied by excellent functional group tolerance.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2023
Tipo del documento:
Article