Facial-onset sensory and motor neuronopathy with myasthenia gravis: A case report.
Medicine (Baltimore)
; 102(46): e34215, 2023 Nov 17.
Article
en En
| MEDLINE
| ID: mdl-37986404
ABSTRACT
RATIONALE Facial-onset sensory and motor neuronopathy (FOSMN) is a greatly rare disease, so far, autopsy evidence that is associated with neurodegenerative. Myasthenia gravis (MG) is an antibody-mediated and complement-involved acquired autoimmune disorder of the post-synaptic neuromuscular junction. There have been few reports about if there is related between the 2. In this study, we present the case of a man who was diagnosed as FOSMN with MG in continuity. PATIENT CONCERNS The patient chief complaints were right-side facial numbness and right-eyelid incomplete closure, followed by slurred speech and dysphagia, and the symptoms gradually progressed. The patient serum was positive for anti-AchR and anti-Titin antibodies. DIAGNOSES The patient was diagnosed FOSMN with MG. INTERVENTIONS:
The patient symptoms were relieved after pyridostigmine bromide and prednisolone treatment.OUTCOMES:
Symptoms have improved. LESSONS Facial-onset sensory and motor neuronopathy and MG have disparate clinical features. Therefore, we reported a rare case in which the 2 conditions concurrently existed. Immune dysfunction might be the pathogenesis of this association, while there is no definite evidence to support it, further studies are needed.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos de Deglución
/
Miastenia Gravis
Límite:
Humans
/
Male
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2023
Tipo del documento:
Article
País de afiliación:
China